Skip to main content

Explore the Journal of Critical Limb Ischemia (JCLI), a quarterly international peer-reviewed journal and online clinical resource for those treating chronic limb threatening ischemia.

Recently Published

At the 2024 SIR Meeting in Salt Lake City, Utah, interventional radiologist Mark Lessne, MD, from Vascular & Interventional Specialists, Charlotte Radiology in Charlotte, North Carolina, presented several sessions, including “Beyond Paclitaxel: A Review of Non-Paclitaxel-Based Antiproliferative Therapies for PAD Management.” We spoke with Dr. Lessne about his presentation and the future of PAD management.

At the 2024 SIR Meeting in Salt Lake City, Utah, Waseem Wahood, MD, MS, from HCA Florida Aventura Hospital, Aventura, Florida, presented results from a study that analyzed 30-day perioperative outcomes from the National Surgical Quality Improvement Project (NSQIP) in patients who received intervention for chronic limb-threatening ischemia (CLTI). We spoke with Dr. Wahood about his study and what the results could mean for patients with CLTI.


Watch as Dr. Thomas Zeller reviews his presentation on the treatment of symptomatic femoropopliteal disease with drug-coated balloons vs bare-metal stents, which he gave at the Amputation Prevention Symposium in August 2023. 


Watch as Barry Katzen, MD, provides an update on what's new with the CLI Global Society and the Journal of Critical Limb Ischemia.


Dr Pliagas discusses his retrospective study, recently published in JCLI, in which he and his co-investigators sought to demonstrate safety and performance of the Terumo Glidesheath Slender for tibiopedal access. Initially, tibiopedal access was considered a very experimental technique, but over the past few years, Dr Pliagas and his colleagues have learned to routinely gain access to vessels from below, using this technique.


Drs Driver and Neville discuss the crucial component of podiatry in the multidisciplinary treatment of CLTI.

Current Issue


Phantom limb pain (PLP) encapsulates the complex spectrum of pain, both physical and psychological. It serves as a reminder of how deeply interconnected our minds and bodies are and how the presence of pain can persist even in the absence of a physical cause. Understanding and treating PLP requires a holistic approach that considers the intricate interplay between the brain, body, and mind. This integrated perspective helps provide more comprehensive and effective relief for those experiencing this challenging condition.

Original Contribution

Phantom limb pain (PLP) is a common complication after major lower extremity amputations (MLEA), occurring in approximately 85% of patients. PLP significantly affects amputees’ mobility, ability to perform tasks of daily living, and overall quality of life (QoL). Previous studies have discussed surgical treatments for PLP that can improve ambulation and mobility after MLEA. The authors describe 3 patients who underwent peripheral nerve repair PNR to alleviate PLP and reported decreased pain and improved QoL.

Original Contribution

Despite a recent increase in research efforts regarding disparities in peripheral arterial disease/critical limb-threatening ischemia (PAD/CLTI), few studies have focused on minority and women participation in late-breaking clinical investigations exploring various treatments for PAD/CLTI. The authors seek to explore the representation of minority groups and women in clinical studies evaluating the usage of drug-coated balloons for treatment in PAD/CLTI.


Intravascular lithotripsy (IVL) has emerged as a vessel preparation device for heavily calcified arteries during endovascular therapies.8 IVL utilizes multiple emitters mounted on a traditional angioplasty balloon catheter to deliver pulsatile acoustic pressure energy. This approach facilitates the fracture of superficial and deep calcium without compromising local soft tissues and minimizes the risk of emboli liberation.9 In this manuscript, the authors provide a comprehensive review of the role of IVL as an adjunct to endovascular revascularization in the treatment of PAD.

Original Contribution

Presence of calcification is a significant risk factor for treatment resistance during endovascular therapy, limiting vessel expansion and increasing rates of complication. The goal of this study is to assess the safety and efficacy of intravascular lithotripsy in the treatment of calcified peripheral arterial lesions in patients with claudication. 

Original Contribution

The pattern of surgical bypass has affected practice in the context of a multidisciplinary limb preservation program. As bypass may be required for limb preservation, such a practice would involve more frequent bypass and increased complexity of bypass performed due to the lack of an autogenous conduit and suitable target artery (“desert foot”), and patients with prior failed endovascular interventions. We investigated this change in the pattern of bypass performed in the context of our limb preservation program. 

Stay in the know

JCLI Newsletter