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Original Contribution

Original Contribution

This is a pilot feasibility study and the objective is to evaluate the safety and effectiveness of the investigational device, IN.PACT 014 drug-coated balloon, compared with standard PTA in patients with CLI with CTOs of BTK arteries. 

Original Contribution

Presence of calcification is a significant risk factor for treatment resistance during endovascular therapy, limiting vessel expansion and increasing rates of complication. The goal of this study is to assess the safety and efficacy of intravascular lithotripsy in the treatment of calcified peripheral arterial lesions in patients with claudication. 

Original Contribution

The pattern of surgical bypass has affected practice in the context of a multidisciplinary limb preservation program. As bypass may be required for limb preservation, such a practice would involve more frequent bypass and increased complexity of bypass performed due to the lack of an autogenous conduit and suitable target artery (“desert foot”), and patients with prior failed endovascular interventions. We investigated this change in the pattern of bypass performed in the context of our limb preservation program. 

Original Contribution

The definition and treatment of CLTI have been evolving, recognizing the importance of early recognition and aggressive treatment required for those patients. In this article, the authors discuss the historical definitions of CLTI and provide an overview of how the management of patients with CLTI has developed, including surgical and endovascular interventions.

Original Contribution

In this study and review, the authors aim to provide a focused evaluation of the influence of SES on the care, prevalence, and treatment of peripheral arterial disease and critical limb-threatening ischemia.

Original Contribution

The objective of this study was to demonstrate the feasibility of subintimal implantation of interwoven nitinol stents in critical limb-threatening ischemia (CLTI) patients with chronically occluded superficial superior artery and popliteal stents.

Original Contribution

This manuscript reports the 36-month results of the Tack-Optimized Balloon Angioplasty (TOBA) II below-the-knee (BTK) study for repair of post-percutaneous transluminal angioplasty (PTA) dissection(s) of the infrapopliteal arteries.

Original Contribution

This study was performed to describe the outcomes of reintervention procedures for a stenotic or occluded percutaneous deep venous arterialization (pDVA) and to compare outcomes following pDVA patients not requiring repeat intervention.

Original Contribution

Retrograde pedal access may allow the treatment of superficial femoral artery occlusive lesions when standard endovascular techniques fail. Here, we aimed to analyze the outcomes of this approach in patients with chronic limb ischemia who had undergone an unsuccessful attempt at revascularization through antegrade access.

Original Contribution

In response to the COVID-19 pandemic, the authors' tertiary referral center implemented guidelines to triage procedures and shift toward telehealth encounters. The aim of this analysis is to evaluate the impact of this alteration in practice pattern on amputation rate and vascular procedural experience for similar time intervals before and during the initial pandemic.

Original Contribution

The authors analyzed data from the NIS to identify all patients ≥18 years admitted with a primary diagnosis of CLTI from 2016 to 2019. Descriptive statistics were used to summarize patient baseline characteristics. Logistic regression models and temporal trends were used to determine predictors of major amputation and MACE.

Original Contribution

This article describes the patient selection criteria, procedural overview, and postoperative surveillance strategies for open lower extremity distal bypass surgery in patients with long-segment superficial femoral artery disease.

Original Contribution

A paradigm shift appears to be occurring with overwhelming evidence of transradial access (TRA) being a safe and feasible approach for peripheral interventions compared to transfemoral access (TFA). Our study explores the additional, multifactorial benefits of TRA regarding perioperative times, radiation, contrast administration, and cost-savings for patients and hospitals.

Original Contribution

The role of real-time, invasive hemodynamic assessment during endovascular therapy for lower extremity peripheral arterial disease (PAD) has not been well established. The purpose of this study was to examine the feasibility of the Navvus microcatheter coupled to the RXi system (ACIST Medical Systems) to measure lower extremity pre- and post-intervention resting and hyperemic translesional systolic pressure gradients (sTPG) and mean distal to proximal pressure gradients (Pd/Pa).

Original Contribution

Focal treatment of post-angioplasty dissections in below-the-knee lesions with the novel Tack Endovascular System might provide an attractive treatment approach that contributes clinical benefit at concurrent cost savings at 2-year follow-up. Further studies are warranted to confirm these exploratory findings.

Original Contribution

The authors completed an observational Michigan Medicare analysis to investigate the rates of peripheral vascular intervention (PVI) via endovascular approach or surgical bypass, as well as the amputation rates for potentially informative trends.

Original Contribution

The purpose of this study was to examine the feasibility of the Navvus microcatheter coupled to the RXi system (ACIST Medical Systems) to measure lower extremity pre- and post-intervention resting and hyperemic translesional systolic pressure gradients (sTPG) and mean distal to proximal pressure gradients (Pd/Pa).

Original Contribution

From January 2018 more aggressive infrainguinal angioplasties were performed in our institution with a focus on establishing straight-in-line flow to the foot. Our aim was to provide data to demonstrate the impact on clinical outcomes, namely, amputation free survival.

Original Contribution

Using this retrospective study, the authors aimed to demonstrate safety and performance of the Terumo Glidesheath Slender for tibiopedal access. 

Original Contribution

The aim of this study was to present results of ultrasound assisted Angio-Seal VIP closure of antegrade access after peripheral arterial procedures. In addition, the technique of closure is illustrated.

Original Contribution

Peripheral artery disease (PAD) represents an important cause of morbidity and mortality worldwide. In general, women are a particularly susceptible population for their sex differences with men in the development of the disease. The pathophysiology, risk factors, clinical presentation, diagnosis, management, outcomes, and quality of life of women with PAD are reviewed herein.

Original Contribution

The study objective is to better define historical graft patency rates and adverse events following surgical bypass for femoral-popliteal arterial disease in patients with and without critical limb ischemia and compare them with contemporary studies.

Original Contribution

The current study describes the underlying rationale, objectives, and methods to explore PAD, CLI, and CKD associations.

Original Contribution

Consecutive patients scheduled for transfemoral TAVI were retrospectively grouped according to vascular access (percutaneous access and surgical cutdown). Primary endpoints were vascular and bleeding complications and 30-day mortality.

Original Contribution

Our study aims to determine whether racial and gender differences exist between Hispanic and non-Hispanic Americans regarding access and treatment for PAD care.

Original Contribution

The objectives of this trial were to evaluate the safety and performance of the temporary stent in treating infrapopliteal arterial disease.

Original Contribution

An evaluation of the technical aspects of the MicroStent (Micro Medical Solutions), a novel device specifically designed for the treatment of chronic limb-threatening ischemia (CLTI) below the knee (BTK) when used as primary treatment or as bailout in patients enrolled in the HEAL study, a postmarket, multicenter, European all-comers observational study.

Original Contribution

The primary objective of this study was to describe a novel classification system to characterize patterns of failure in deep venous arterialization (DVA) and suggest intervention strategies that correlate with these patterns.

Original Contribution

This article seeks to evaluate the effectiveness of the Celt ACD (Vasorum, Ltd) for the closure of antegrade superficial femoral artery access to treat ipsilateral lower-extremity arterial lesions.

Original Contribution

C-reactive protein levels may be reduced with long-term administration of ubiquinone (CoQ10) in patients with chronic ischemic heart disease, but the impact of a short-term period of administration in patients undergoing elective vascular surgery is uncertain.

Original Contribution

Patients with diabetes and critical limb threatening ischemia (CLTI) are at significantly higher risk of limb loss and death. We evaluate the outcomes of orbital atherectomy (OA) for the treatment of CLTI in patients with and without diabetes.

Original Contribution

Our study aim was to investigate the complete wound-healing rate in patients with chronic limb-threatening ischemia after endovascular revascularization, comparing the effectiveness of wound care management by plastic surgeons with other medical specialists.

Original Contribution

We performed a meta-analysis of randomized controlled trials investigating the clinical outcomes of patients undergoing percutaneous revascularization with DCB vs percutaneous transluminal angioplasty (PTA) of infrapopliteal arteries.

Original Contribution

This study investigates the cost-effectiveness of bypass surgery vs endovascular intervention in CLTI with femoropopliteal lesions.

Original Contribution

Our study objective was to explore the potential cost-effectiveness of treatment with the LimFlow pDVA system (LimFlow SA) in the United States healthcare system.

Original Contribution

The study objective was to evaluate the safety and efficacy of below-the-ankle intervention in the office-based setting for treatment of chronic limb-threatening ischemia.

Original Contribution

The purpose of this study was to investigate the effect of below-the-ankle (BTA) angioplasty on angiographic pedal arch patency and its association with clinical outcomes in patients with chronic critical limb ischemia (CLI).

Original Contribution

The study objective is to determine whether selective coronary revascularization following lower-extremity revascularization can improve long-term survival of patients with critical limb threatening ischemia.

Original Contribution

Two prespecified literature searches were conducted via Ovid utilizing the following databases: MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews (CDSR). We selected studies reporting amputation-free survival (AFS) in patients with non-revascularizable Rutherford category 5/6 CLI at a minimum follow-up of 6 months.

Original Contribution

Despite medical advancements, PAD and CLI continue to increase globally. Treatment for PAD/CLI varies widely and patients with CTOs may be more challenging to treat, requiring specialized crossing techniques and modalities. The objective of this study was to determine the relationship between patients diagnosed with PAD/CLI, with CTOs, and subsequent long-term outcomes. 

Original Contribution

This randomized, controlled trial was designed to compare the rate of postangiographic contrast-induced nephropathy between the intra-arterial injections of carbon dioxide and the iodinated contrast agent.

Original Contribution

Amputation as the initial treatment of choice remains prevalent despite advances in revascularization techniques and medical therapy. We evaluated the 7-year mortality of patients undergoing major and minor lower-extremity amputations and determined the impact of risk factors on long-term mortality.

Original Contribution

We review here the mechanism of action of OA, supporting clinical study evidence, and corresponding economic analyses.

Review

This review serves to introduce the most recent data with a factor Xa inhibitor as a novel antithrombotic strategy for PAD. 

Original Contribution

Previous studies have suggested that Black patients with peripheral artery disease (PAD) may have worse outcomes than White patients. The aim of this study was to determine whether there are racial differences in outcomes of patients with PAD undergoing endovascular treatment.

Original Contribution

This analysis seeks to describe the technique of ultrasound-assisted percutaneous superficial femoral arterial access closure with a Mynx device (Cordis Corporation). The study aim was to demonstrate the technical considerations, benefits, efficacy, and safety of this technique.

Original Contribution

Below-the-knee peripheral arterial disease more often presents as critical limb ischemia. Endovascular revascularization strategies continue to evolve to achieve long-term limb-salvage outcomes. A single-center experience with optical coherence tomography-guided atherectomy using Pantheris SV (Avinger) is reported.

Original Contribution

The Outback device (Cordis) enables true lumen re-entry during subintimal recanalization of CTOs. This study compared outcomes of patients who underwent subintimal recanalization of lower-extremity arterial CTOs utilizing the Outback device via antegrade and retrograde approaches.

Original Contribution

The aim of the study was to evaluate the safety and short-term efficacy of the Ranger paclitaxel-coated balloon (PCB; Boston Scientific) in the setting of CLI. 

Original Contribution

To understand the impact of fluence and repetition rate on outcomes of superficial femoral artery and popliteal artery laser atherectomy based on lesion type (calcific, homogenous, heterogeneous, and restenosis).