This is a pilot feasibility study and the objective is to evaluate the safety and effectiveness of the investigational device, IN.PACT 014 drug-coated balloon, compared with standard PTA in patients with CLI with CTOs of BTK arteries.
This study was performed to describe the outcomes of reintervention procedures for a stenotic or occluded percutaneous deep venous arterialization (pDVA) and to compare outcomes following pDVA patients not requiring repeat intervention.
Retrograde pedal access may allow the treatment of superficial femoral artery occlusive lesions when standard endovascular techniques fail. Here, we aimed to analyze the outcomes of this approach in patients with chronic limb ischemia who had undergone an unsuccessful attempt at revascularization through antegrade access.
In response to the COVID-19 pandemic, the authors' tertiary referral center implemented guidelines to triage procedures and shift toward telehealth encounters. The aim of this analysis is to evaluate the impact of this alteration in practice pattern on amputation rate and vascular procedural experience for similar time intervals before and during the initial pandemic.
The authors analyzed data from the NIS to identify all patients ≥18 years admitted with a primary diagnosis of CLTI from 2016 to 2019. Descriptive statistics were used to summarize patient baseline characteristics. Logistic regression models and temporal trends were used to determine predictors of major amputation and MACE.
This article describes the patient selection criteria, procedural overview, and postoperative surveillance strategies for open lower extremity distal bypass surgery in patients with long-segment superficial femoral artery disease.
A paradigm shift appears to be occurring with overwhelming evidence of transradial access (TRA) being a safe and feasible approach for peripheral interventions compared to transfemoral access (TFA). Our study explores the additional, multifactorial benefits of TRA regarding perioperative times, radiation, contrast administration, and cost-savings for patients and hospitals.
The role of real-time, invasive hemodynamic assessment during endovascular therapy for lower extremity peripheral arterial disease (PAD) has not been well established. The purpose of this study was to examine the feasibility of the Navvus microcatheter coupled to the RXi system (ACIST Medical Systems) to measure lower extremity pre- and post-intervention resting and hyperemic translesional systolic pressure gradients (sTPG) and mean distal to proximal pressure gradients (Pd/Pa).
Focal treatment of post-angioplasty dissections in below-the-knee lesions with the novel Tack Endovascular System might provide an attractive treatment approach that contributes clinical benefit at concurrent cost savings at 2-year follow-up. Further studies are warranted to confirm these exploratory findings.
The authors completed an observational Michigan Medicare analysis to investigate the rates of peripheral vascular intervention (PVI) via endovascular approach or surgical bypass, as well as the amputation rates for potentially informative trends.
The purpose of this study was to examine the feasibility of the Navvus microcatheter coupled to the RXi system (ACIST Medical Systems) to measure lower extremity pre- and post-intervention resting and hyperemic translesional systolic pressure gradients (sTPG) and mean distal to proximal pressure gradients (Pd/Pa).
From January 2018 more aggressive infrainguinal angioplasties were performed in our institution with a focus on establishing straight-in-line flow to the foot. Our aim was to provide data to demonstrate the impact on clinical outcomes, namely, amputation free survival.
Using this retrospective study, the authors aimed to demonstrate safety and performance of the Terumo Glidesheath Slender for tibiopedal access.
Peripheral artery disease (PAD) represents an important cause of morbidity and mortality worldwide. In general, women are a particularly susceptible population for their sex differences with men in the development of the disease. The pathophysiology, risk factors, clinical presentation, diagnosis, management, outcomes, and quality of life of women with PAD are reviewed herein.
The study objective is to better define historical graft patency rates and adverse events following surgical bypass for femoral-popliteal arterial disease in patients with and without critical limb ischemia and compare them with contemporary studies.
The current study describes the underlying rationale, objectives, and methods to explore PAD, CLI, and CKD associations.
Consecutive patients scheduled for transfemoral TAVI were retrospectively grouped according to vascular access (percutaneous access and surgical cutdown). Primary endpoints were vascular and bleeding complications and 30-day mortality.
Our study aims to determine whether racial and gender differences exist between Hispanic and non-Hispanic Americans regarding access and treatment for PAD care.
The objectives of this trial were to evaluate the safety and performance of the temporary stent in treating infrapopliteal arterial disease.
An evaluation of the technical aspects of the MicroStent (Micro Medical Solutions), a novel device specifically designed for the treatment of chronic limb-threatening ischemia (CLTI) below the knee (BTK) when used as primary treatment or as bailout in patients enrolled in the HEAL study, a postmarket, multicenter, European all-comers observational study.
The primary objective of this study was to describe a novel classification system to characterize patterns of failure in deep venous arterialization (DVA) and suggest intervention strategies that correlate with these patterns.
This article seeks to evaluate the effectiveness of the Celt ACD (Vasorum, Ltd) for the closure of antegrade superficial femoral artery access to treat ipsilateral lower-extremity arterial lesions.
C-reactive protein levels may be reduced with long-term administration of ubiquinone (CoQ10) in patients with chronic ischemic heart disease, but the impact of a short-term period of administration in patients undergoing elective vascular surgery is uncertain.
Patients with diabetes and critical limb threatening ischemia (CLTI) are at significantly higher risk of limb loss and death. We evaluate the outcomes of orbital atherectomy (OA) for the treatment of CLTI in patients with and without diabetes.
Our study aim was to investigate the complete wound-healing rate in patients with chronic limb-threatening ischemia after endovascular revascularization, comparing the effectiveness of wound care management by plastic surgeons with other medical specialists.
We performed a meta-analysis of randomized controlled trials investigating the clinical outcomes of patients undergoing percutaneous revascularization with DCB vs percutaneous transluminal angioplasty (PTA) of infrapopliteal arteries.
This study investigates the cost-effectiveness of bypass surgery vs endovascular intervention in CLTI with femoropopliteal lesions.
Our study objective was to explore the potential cost-effectiveness of treatment with the LimFlow pDVA system (LimFlow SA) in the United States healthcare system.
The study objective was to evaluate the safety and efficacy of below-the-ankle intervention in the office-based setting for treatment of chronic limb-threatening ischemia.
The purpose of this study was to investigate the effect of below-the-ankle (BTA) angioplasty on angiographic pedal arch patency and its association with clinical outcomes in patients with chronic critical limb ischemia (CLI).
The study objective is to determine whether selective coronary revascularization following lower-extremity revascularization can improve long-term survival of patients with critical limb threatening ischemia.
Two prespecified literature searches were conducted via Ovid utilizing the following databases: MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews (CDSR). We selected studies reporting amputation-free survival (AFS) in patients with non-revascularizable Rutherford category 5/6 CLI at a minimum follow-up of 6 months.
Despite medical advancements, PAD and CLI continue to increase globally. Treatment for PAD/CLI varies widely and patients with CTOs may be more challenging to treat, requiring specialized crossing techniques and modalities. The objective of this study was to determine the relationship between patients diagnosed with PAD/CLI, with CTOs, and subsequent long-term outcomes.
This randomized, controlled trial was designed to compare the rate of postangiographic contrast-induced nephropathy between the intra-arterial injections of carbon dioxide and the iodinated contrast agent.
Amputation as the initial treatment of choice remains prevalent despite advances in revascularization techniques and medical therapy. We evaluated the 7-year mortality of patients undergoing major and minor lower-extremity amputations and determined the impact of risk factors on long-term mortality.
We review here the mechanism of action of OA, supporting clinical study evidence, and corresponding economic analyses.
This review serves to introduce the most recent data with a factor Xa inhibitor as a novel antithrombotic strategy for PAD.
Previous studies have suggested that Black patients with peripheral artery disease (PAD) may have worse outcomes than White patients. The aim of this study was to determine whether there are racial differences in outcomes of patients with PAD undergoing endovascular treatment.
This analysis seeks to describe the technique of ultrasound-assisted percutaneous superficial femoral arterial access closure with a Mynx device (Cordis Corporation). The study aim was to demonstrate the technical considerations, benefits, efficacy, and safety of this technique.
Below-the-knee peripheral arterial disease more often presents as critical limb ischemia. Endovascular revascularization strategies continue to evolve to achieve long-term limb-salvage outcomes. A single-center experience with optical coherence tomography-guided atherectomy using Pantheris SV (Avinger) is reported.
The Outback device (Cordis) enables true lumen re-entry during subintimal recanalization of CTOs. This study compared outcomes of patients who underwent subintimal recanalization of lower-extremity arterial CTOs utilizing the Outback device via antegrade and retrograde approaches.
The aim of the study was to evaluate the safety and short-term efficacy of the Ranger paclitaxel-coated balloon (PCB; Boston Scientific) in the setting of CLI.
To understand the impact of fluence and repetition rate on outcomes of superficial femoral artery and popliteal artery laser atherectomy based on lesion type (calcific, homogenous, heterogeneous, and restenosis).